منابع مشابه
Signal transduction in mesangial cells.
Phenotype, growth, and functional characteristics of glomerular mesangial "myofibroblasts" are under the control of multiple hormones, vasoactive agents, autacoids, and cytokines. Several parallel signal transduction pathways couple receptor occupancy with functional changes, including phospholipases C, A2, and D breakdown of membrane phospholipids, and adenylate/guanylate cyclase activation. C...
متن کاملTGF- signal transduction and mesangial cell fibrogenesis
Schnaper, H. William, Tomoko Hayashida, Susan C. Hubchak, and Anne-Christine Poncelet. TGFsignal transduction and mesangial cell fibrogenesis. Am J Physiol Renal Physiol 284: F243–F252, 2003; 10.1152/ajprenal.00300.2002.—Transforming growth factor(TGF) is closely associated with progressive renal fibrosis. Significant progress has been accomplished in determining the cellular signaling pathways...
متن کاملcADP-ribose/ryanodine channel/Ca2+-release signal transduction pathway in mesangial cells.
Signaling via release of Ca2+ from intracellular stores is mediated by several systems, including the inositol 1,4,5-trisphosphate (IP3) and cADP-ribose (cADPR) pathway. We recently discovered a high capacity for cADPR synthesis in rat glomeruli and cultured mesangial cells (MC). We sought to determine whether 1) cADPR synthesis in MC is regulated by cytokines and hormones, 2) ryanodine recepto...
متن کاملcADP-ribose/ryanodine channel/Ca-release signal transduction pathway in mesangial cells
Yusufi, Ahad N. K., Jingfei Cheng, Michael A. Thompson, Thomas P. Dousa, Gina M. Warner, Henry J. Walker, and Joseph P. Grande. cADP-ribose/ryanodine channel/Ca21-release signal transduction pathway in mesangial cells. Am J Physiol Renal Physiol 281: F91–F102, 2001.—Signaling via release of Ca21 from intracellular stores is mediated by several systems, including the inositol 1,4,5-trisphosphate...
متن کاملSignal transduction in T cells.
Rapid progress was made during the past year in the delineation of the nature of the initial biochemical events triggered by the T-cell antigen receptor. Antigen-mediated activation of phospholipase C was demonstrated to require protein tyrosine phosphorylation and, most surprising, activation of the Ras family of signal transduction molecules was shown to closely follow stimulation of the T-ce...
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ژورنال
عنوان ژورنال: Journal of the American Society of Nephrology
سال: 1992
ISSN: 1046-6673,1533-3450
DOI: 10.1681/asn.v210s100